PEG-MGF (Pegylated Mechano Growth Factor) – Research Peptide

PEG-MGF (Pegylated Mechano Growth Factor) is a synthetic variant of Mechano Growth Factor (MGF), a splice variant of Insulin-like Growth Factor-1 (IGF-1). MGF is expressed in muscle and other tissues following mechanical stress in experimental models.

Pegylation (PEG attachment) is used in research formulations to modify peptide stability and extend experimental half-life compared to the non-pegylated fragment.

Research Use Only: This material is supplied strictly for laboratory developmental research use. It is not intended for human or veterinary consumption.

Scientific Classification

• Common Name: PEG-MGF
• Synonyms: Pegylated Mechano Growth Factor; PEG-IGF-1 Ec; PEG-IGF-1Ea; PEG myotrophin
• Classification: Synthetic peptide; IGF-1 splice variant analog
• Parent Molecule: Insulin-like Growth Factor-1 (IGF-1)
• Peptide Type: Pegylated 24-amino acid C-terminal fragment (MGF derivative)

Chemical & Structural Information

• Base Peptide Molecular Weight: ~2,860–2,948 Da (24-amino acid fragment)
• Total Molecular Weight: Varies depending on PEG chain length (commonly ~2,888.2 Da or higher when PEG mass is included)
• Molecular Formula (Base Peptide): C₁₂₁H₂₀₀N₄₂O₃₉
• Structural Modification: Polyethylene glycol (PEG) conjugation for enhanced stability in research models

Research Context

Within controlled laboratory environments, PEG-MGF has been examined in studies involving:

• IGF-1 receptor signaling pathway models
• Muscle cell differentiation and proliferation research
• Satellite cell activation studies (in vitro)
• Peptide half-life and stability investigations
• Splice-variant structure–activity relationship (SAR) analysis

MGF-related peptides are frequently referenced in research examining mechanical stress signaling pathways and tissue adaptation models in experimental systems.

No therapeutic or medical claims are made. All descriptions above are limited strictly to laboratory and investigational research contexts.

Product Classification

• Category: Synthetic Research Peptide (Pegylated)
• Form: Research-grade raw material (refer to product label for preparation details)
• Intended Use: Laboratory and developmental research only

Regulatory Status

This product is not approved by the U.S. Food and Drug Administration (FDA) for the diagnosis, treatment, cure, or prevention of any disease.

This material is sold exclusively for laboratory research purposes.

FDA Disclaimer

The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease.

The information in this website is for educational purposes only and is not intended as medical or research advice.

Research Use Only

All products are for laboratory developmental research USE ONLY. Products are not for human consumption. Use of these products in such a manner other than research violates the terms of service.

Legal Disclaimer

This product is sold as a pure compound for research purposes only and is not for use as a dietary supplement. Please refer to the terms and conditions prior to purchase.

Safety Information

Keep this product out of the reach of children. This material has limited research available and may result in adverse effects if improperly handled or consumed.

This product is not a dietary supplement but a pure substance sold as a raw material. We attest to the quality, purity, and description of the materials we provide. This product is intended for persons with the knowledge and equipment to safely handle laboratory materials.

You agree to indemnify us for any adverse effects that may arise from improper handling and/or consumption of this product.

The articles and information on products that may be found on this website are provided exclusively for informational and educational purposes. These items are not pharmaceuticals or medications, and the Food and Drug Administration has not given permission for the treatment or prevention of any disease, medical condition, or ailment using them.