Melanotan 1 (Afamelanotide) – Research Grade Peptide

What is Melanotan 1?

Melanotan 1, scientifically known as Afamelanotide and structurally designated as [Nle4, D-Phe7]-α-MSH, is a synthetic 13-amino acid analog of alpha-melanocyte-stimulating hormone (α-MSH). It is classified as a melanocortin receptor agonist and peptide hormone analog used in scientific research involving melanocortin system signaling.

Melanotan 1 contains two key structural substitutions designed to enhance molecular stability and receptor affinity:

• Norleucine (Nle) at position 4

• D-Phenylalanine (D-Phe) at position 7

These modifications improve resistance to enzymatic degradation and increase biological activity in laboratory models.

Scientific Classification

• Generic Name: Afamelanotide

• Chemical Name: [Nle4, D-Phe7]-α-MSH

• Peptide Length: 13 amino acids

• Classification: Peptide hormone analog | Melanocortin receptor agonist | Polypeptide

• Molecular Formula: C78H111N21O19

• Molecular Weight: ~1646.87 g/mol

• Exact Mass: ~1645.84 Da

Amino Acid Sequence

Research Context

Melanotan 1 is studied for its selective activity at melanocortin receptors, particularly MC1R, within experimental research settings. Its structure allows researchers to investigate melanogenesis pathways, receptor signaling mechanisms, and peptide stability dynamics under controlled laboratory conditions.

A pharmaceutical form of Afamelanotide is approved under the brand name Scenesse® for a specific rare condition. XXXPeptides does not sell pharmaceutical products or sell to patients. Our materials are supplied strictly for laboratory research use.

Quality & Research Standards

XXXPeptides supplies Melanotan 1 as a research-grade compound intended exclusively for laboratory investigation and developmental research. Each batch is handled under strict quality standards to ensure purity and compound integrity.

This material is provided as a pure compound and is not formulated, labeled, or sold as a dietary supplement, pharmaceutical, or therapeutic product.

Regulatory & Safety Information

FDA Disclaimer

The statements made on this website have not been evaluated by the U.S. Food and Drug Administration. The products offered by this company are not intended to diagnose, treat, cure, or prevent any disease.

All information provided is for educational purposes only and is not medical or clinical advice.

Research Use Only Notice

All products sold by XXXPeptides are intended for laboratory developmental research use only.

• Not for human consumption

• Not for veterinary use

• Not for use as a dietary supplement

• Not for resale as a finished product

Use of these materials outside of laboratory research violates our Terms and Conditions.

Legal Disclaimer

This product is sold as a pure research compound. It is not a dietary supplement, food, cosmetic, or pharmaceutical product.

By purchasing, the buyer affirms that they are qualified and equipped to safely handle laboratory research materials and agrees to indemnify XXXPeptides against misuse.

Safety Information

• Keep out of reach of children

• For use only by trained laboratory professionals

• Limited long-term safety data exists outside controlled research environments

• Improper handling or use may result in adverse effects

This product is sold as a raw material for research purposes only.

Research