Kisspeptin-10 10mg

Research Use Only

Overview

Kisspeptin-10 (Kp-10) is a synthetic decapeptide representing the minimal active fragment derived from the KISS1 gene product. It is recognized in research literature as the shortest functional sequence capable of activating the kisspeptin receptor (GPR54 / KISS1R).

A C-terminal phenylalanine amidation is essential for receptor interaction in experimental systems.

For laboratory research use only. Not for human or veterinary use.

Key Specifications

• Common Name: Kisspeptin-10
• Abbreviation: Kp-10
• Classification: Synthetic decapeptide
• Biological Origin: Functional fragment of KISS1 gene product
• Receptor Target: KISS1R (GPR54)
• Peptide Length: 10 amino acids
• Molecular Formula: C63H83N17O14
• Molecular Weight: ~1302.45 g/mol
• Form: Research-grade peptide powder

Amino Acid Sequence

YNWNSFGLRF-NH₂
(H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-amide)

Structural Feature

• C-terminal amidation (–NH₂) is critical for receptor binding activity in research models
• Minimal active fragment of the full kisspeptin peptide family

Research Focus

In laboratory environments, Kisspeptin-10 is commonly studied in:

• KISS1R (GPR54) receptor activation models
• Hypothalamic–pituitary–gonadal (HPG) axis signaling research
• Neuroendocrine pathway regulation studies
• Peptide–receptor binding kinetics
• Structure–activity relationship (SAR) analysis

All applications are strictly limited to in vitro and experimental research systems.

Biological Context (Research Only)

Kisspeptin-10 is widely used as a minimal functional peptide fragment for studying receptor activation mechanisms within neuroendocrine signaling pathways.

Storage & Handling

• Store at -20°C
• Protect from moisture and light
• Use sterile laboratory handling procedures
• Avoid repeated freeze–thaw cycles

Regulatory Notice

Kisspeptin-10 is not approved by the U.S. Food and Drug Administration (FDA) for medical, therapeutic, or diagnostic use.
It is supplied strictly as a research compound for laboratory use only.

Safety & Compliance

• Not for human consumption
• Not for veterinary use
• Not for clinical or diagnostic applications
• Not a dietary supplement
• For qualified laboratory personnel only

Improper handling may result in risk. Use only in controlled laboratory environments with appropriate safety procedures.