Melanotan 1 (Afamelanotide) | 10mg | Research Use Only

13 amino acids. Two changes from natural alpha-MSH. That's the whole idea behind Melanotan 1.

The scientific name is Afamelanotide. The structural label is [Nle4, D-Phe7]-α-MSH. It's a synthetic analog not the hormone itself. An analog. Built to mimic alpha-melanocyte-stimulating hormone but with two specific amino acid swaps.

Position 4: Norleucine (Nle) replaces methionine.
Position 7: D-Phenylalanine (D-Phe) goes in.

Why those two? Both changes slow enzymatic breakdown. They also increase binding activity at melanocortin receptors in lab models. Researchers study this to see what the substitutions actually do how much they change receptor behavior versus the native peptide.

Lab only. Not for humans. Not for animals.

What it's classified as:

Generic name: Afamelanotide
Chemical name: [Nle4, D-Phe7]-α-MSH
Length: 13 amino acids
Type: Peptide hormone analog, melanocortin receptor agonist
Formula: C78H111N21O19
Weight: ~1646.87 g/mol
Exact mass: ~1645.84 Da
Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2

What the research covers:

MC1R binding is the main focus. Most studies using Melanotic 1 look at melanocortin receptor signaling specifically how the two structural changes affect selectivity and potency. Melanogenesis pathway work comes up too. Peptide stability research uses it as a model case. The substitutions make it useful for comparing modified versus native peptide behavior side by side.

One thing to be clear on: a pharmaceutical version called Scenesse exists. It's FDA-approved for a rare condition. That's not this. XXXPeptides sells raw lab compounds not pharmaceuticals, not patient products. Different thing entirely.

Researchers working on GPCR neuropeptide signaling may also find our VIP 10mg Vasoactive Intestinal Peptide research neuropeptide useful.

Product info:

Name: Melanotic 1 / Afamelanotide
Form: Research-grade compound
Amount: 10mg
Use: Lab research only

Each batch is tested for purity. Supplied as a raw compound not a supplement, not a drug, not a cosmetic.

Legal:

Not FDA approved. Can't diagnose, treat, cure, or prevent anything. Lab research only. Period.

Read the terms before ordering. Buying means you're qualified to handle lab materials and accept our indemnification terms.

Safety:

Lab training needed. Right equipment required. Don't consume it. Keep away from kids. Not much long-term safety data exists. Mishandling can cause harm.